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Comments Received DEA received 264 comments regarding the NPRM.Two hundred thirty- one commenters supported the NPRM, 33 commenters opposed the rulemaking.These commenters explained that, currently, they must either drive to their practitioners, which is difficult for them, or must find someone to drive them because they cannot drive themselves due to their condition.They noted that arranging rides is often difficult and that the drive to a practitioner may be several hours each way.DATES: Effective Date: This rule is effective December 19, 2007. Caverly, Chief, Liaison and Policy Section, Office of Diversion Control, Drug Enforcement Administration, Washington, DC 20537, Telephone (202) 307-7297.SUPPLEMENTARY INFORMATION: Background On September 6, 2006, the Drug Enforcement Administration (DEA) published in the Federal Register a Notice of Proposed Rulemaking (NPRM) (71 FR 52724) proposing to amend its regulations to allow practitioners to provide individual patients with multiple prescriptions, to be filled sequentially, for the same schedule II controlled substance, with such multiple prescriptions having the combined effect of allowing a patient to receive over time up to a 90- day supply of that controlled substance.An in-depth discussion of the issues raised by commenters and DEA's responses to those comments follows.

: Commenters who identified themselves as practitioners who prescribe controlled substances were, for the most part, strongly supportive of the proposed rule.

This latter perspective of some commenting practitioners is addressed further below.

: Commenters who identified themselves as pharmacists were, for the most part, supportive of the proposed rule.

These commenters stated that issuing multiple prescriptions for sequential filling for schedule II controlled substances would reduce the quantity of those controlled substances dispensed to a patient at any one time.

They argued that this reduced quantity could reduce the potential for abuse or diversion of these controlled substances.

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